Jeff Larish provide the first boost of offense for the Pirates, drilling a two-run single against Red Sox knuckleballer Steven Wright.
Making his second start of Spring Training, Red Sox ace Jon Lester fired three shutout innings, walking one and striking out two.
"I was able to do the same things that we talked about early on -- staying tall, driving the ball downhill, and I was able to do that tonight," Lester said. "And I was able to mix in a few other pitches. I threw one, maybe two changeups, a couple of curveballs and a couple of cutters. It was nice to break them all out and get good results. It's always nice when you're working on things to get good results."
Dustin Pedroia went 2-for-2 with a walk while scoring a run and driving in two.
Mike Napoli made his debut in a Red Sox uniform, going 1-for-2 with an RBI and making several plays at his new primary position -- first base.
"I felt good," said Napoli. "I felt comfortable over there. I should, after all the work we've put in on the backfields and just working on it. Everything felt good, my legs felt good and I was happy to be in there."
Rubby De La Rosa, Boston's promising right-hander, fired two solid innings, striking out two.
Up next: The Pirates travel to Lakeland to play a 1:05 p.m. ET game against the Tigers on Saturday. Jeanmar Gomez will make his second start for the Pirates, and he will be followed by Jared Hughes, Kris Johnson, Mark Melancon and Ryan Reid. Johnson is the lone left-handed pitcher among them. Drew Smyly will start for the Tigers.
Ian Browne is a reporter for MLB.com. Read his blog, Brownie Points, and follow him on Twitter @IanMBrowne. This story was not subject to the approval of Major League Baseball or its clubs.