Hague connected for his first homer -- a two-run bomb off Kevin Gregg -- and ended with three RBIs on the night. Presley went 3-for-3 with two RBIs and two runs scored, and Marte went 3-for-3 with two runs scored.
"Speed will be a plus for us, by aggressiveness or surprise," said Pirates manager Clint Hurdle. "If you just hustle down the line, beat a relay throw on a double play, good things happen. Speed shows up every day."
Gregg did settle down, collecting three straight strikeouts to end the third, but new Orioles reliever Matt Lindstrom struggled in his debut in the fourth, allowing three runs on three hits and a walk to let Pittsburgh extend its lead.
The Pirates scored three runs off Orioles starter Brian Matusz, who allowed six hits and struck out three in his first spring start. The 25-year-old Matusz, who is competing for a rotation spot, looked better than his line indicated, and his fastball was consistently clocked in the high 80s to low 90s. He struck out three over two innings of work.
"The Pirates executed really well and took advantage of the mistakes I made and put the ball in play," said Matusz. "But overall, I felt like I attacked the zone really well and stuck to my game plan."
Former Orioles pitcher and Pirates bullpen hopeful Jo-Jo Reyes allowed one run over a five-out start. The O's scored off him in the bottom of the first when right fielder Starling Marte misjudged a routine fly ball, allowing Adam Jones to cross the plate.
The Pirates, successful last season against left-handed starters (23-22), are getting a head start on improving on that. They'll be back at McKechnie Field at 1:05 p.m. ET on Tuesday to host the Yankees to face their fourth consecutive southpaw starter in as many exhibitions -- CC Sabathia. Kevin Correia will make his first spring appearance in a duel between 2011 Opening Day starters. Following Correia, Ryota Igarashi and Juan Cruz will continue their duel for a bullpen spot; each non-roster invitee is slated to pitch his second inning of the spring.
The Orioles will travel to Fort Myers, Fla., to take on the Red Sox in their new spring home. Left-hander Dana Eveland will get the start and will go two innings, followed by right-hander Chris Tillman. Both pitchers are vying for a spot on the Opening Day roster and will be making their first spring starts in the 1:35 p.m. ET game.
Brittany Ghiroli is a reporter for MLB.com. Read her blog, Britt's Bird Watch, and follow her on Twitter @britt_ghiroli. This story was not subject to the approval of Major League Baseball or its clubs.