The hand injury, which Lee sustained when he was hit by a pitch on Aug. 3, kept the first baseman out for four straight games. He returned to the lineup Monday and played again Tuesday before notifying the training staff Wednesday morning that his hand was too sore to handle another day on the field.
General manager Neal Huntington said the club is "a long ways away" from considering disabled-list time for Lee, who was acquired from the Orioles on July 30. That said, there is also no timetable for how long the Pirates expect this discomfort in Lee's hand to linger.
"He's got a bad bruise in there," Huntington said. "He's got some soreness. He's a veteran. He knows what he can work through and what he can't. We certainly don't want to put him in harm's way. What he can tolerate, what he can do, he knows. We have to make sure we respect that."
Lee, who had an MRI done on his hand last weekend, is not currently scheduled to have any additional tests.