Reds left fielder Jonny Gomes hit a hard smash that Pirates third baseman Delwyn Young corralled, but he threw the ball well wide of the bag, forcing Pearce to dive to the left field side of the base.
As Gomes headed for second base, Pearce chased down the ball, but after retrieving it and throwing to second, he appeared to twist his right ankle. He hobbled around for a few minutes, and Pittsburgh manager John Russell and team trainer Brad Henderson emerged from the dugout to check on him. But after a short delay, Pearce returned to his position and the game resumed.
After the Pirates batted in the top of the third inning, though, Russell took Pearce out of the game.